Review Article
Research Trends and Hotspots in Levodopa-induced Dyskinesia: A Bibliometric Analysis (2015-2024)
Haixin Shi
,
Jiaxuan Chen,
Xinman Fan,
Xiaoxin Xu,
Xiaohong Xu*
Issue:
Volume 11, Issue 1, March 2026
Pages:
1-13
Received:
25 January 2026
Accepted:
12 February 2026
Published:
27 February 2026
Abstract: Levodopa is a core therapeutic agent for Parkinson's disease (PD), while its long-term administration often leads to levodopa-induced dyskinesia (LID), which significantly compromises patients’ quality of life. This study utilizes bibliometric analysis to examine research trends in LID over the past decade, with the aim of identifying key research hotspots and prospective directions in the field. Relevant publications published between 2015 and 2024 were retrieved from the Web of Science and PubMed databases. A total of 691 articles were ultimately included for systematic analysis. Visual analytic techniques were applied using VOSviewer and CiteSpace to examine publication trends, contributions by countries and institutions, author collaboration networks, and keyword clustering. The annual number of publications in LID research exhibited a declining trend over the study period, with a peak in 2015. The United States and institution CNRS (Centre National de la Recherche Scientifique) contributed most significantly. Movement Disorders was the leading journal in both publication volume (54 articles) and citations (2,369). Author Huot P. was the most prolific (25 articles). Keyword analysis identified core themes encompassing "disease-drug-complication-intervention-model." The knowledge structure developed around key clusters: disease models and Parkinson Disease/Drug Therapy. Trend analysis revealed a move from retrospective etiology to refined safety assessments and mechanism-driven interventions. This study outlines the global research landscape and developmental trends in LID, thereby providing a theoretical foundation for future investigations into non-invasive brain stimulation, precision medicine, and novel drug therapies. Further research should emphasize early LID prediction, targeted treatments, and multidisciplinary management.
Abstract: Levodopa is a core therapeutic agent for Parkinson's disease (PD), while its long-term administration often leads to levodopa-induced dyskinesia (LID), which significantly compromises patients’ quality of life. This study utilizes bibliometric analysis to examine research trends in LID over the past decade, with the aim of identifying key research ...
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Research Article
Geographical and Socioeconomic Inequalities in the Utilization of Maternal Healthcare Services in Nigeria
Issue:
Volume 11, Issue 1, March 2026
Pages:
14-30
Received:
6 February 2026
Accepted:
20 February 2026
Published:
4 March 2026
Abstract: Maternal healthcare utilization remains suboptimal in Nigeria, with persistent socioeconomic and geographical disparities undermining progress toward reducing maternal morbidity and mortality. This study aims to assess the geographical and socioeconomic inequalities of maternal healthcare utilization in Nigeria. Maternal healthcare utilization in Nigeria remains suboptimal, with persistent socioeconomic and geographical disparities hindering progress in reducing maternal morbidity and mortality. This study assessed inequalities in the utilization of antenatal care (ANC4+), facility-based delivery (FBD), and postnatal care (PNC) using data from the 2018 Nigeria Demographic and Health Survey. Socioeconomic inequalities were examined using Erreygers Normalized Concentration Indices (ENCI) and concentration curves disaggregated by region and residence, while decomposition analysis identified key drivers. Findings revealed significant pro-rich inequalities across all services. Facility-based delivery showed the widest gaps (urban ENCI = 0.295; rural = 0.121), particularly in the Northwest (0.398) and Northeast (0.254). ANC4+ visits displayed moderate inequality, highest in the Northwest (0.169). PNC showed minimal inequality, with ENCI values near zero. Wealth status was the strongest contributor to inequality, supported by education, parity, and religion, while age, marital status, employment, autonomy, and insurance played minor roles. Although overall utilization was higher in urban areas, inequality was more pronounced there, highlighting deep intra-urban socioeconomic divides. Substantial socioeconomic and geographic inequities persist in maternal healthcare utilization in Nigeria. Targeted interventions addressing financial, educational, and sociocultural barriers, especially in northern and urban-poor populations, are crucial to narrowing gaps and improving maternal outcomes.
Abstract: Maternal healthcare utilization remains suboptimal in Nigeria, with persistent socioeconomic and geographical disparities undermining progress toward reducing maternal morbidity and mortality. This study aims to assess the geographical and socioeconomic inequalities of maternal healthcare utilization in Nigeria. Maternal healthcare utilization in N...
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